| ARTICLES | Volume 1, Issue 8, Pages 274-279 (October 2015)

Research Article        RISK FACTORS OF BEING ACUTE HEPATITIS B SURFACE ANTIGENEMIA IN BANGLADESHI ADULT PATIENTS          | M Moyen Uddin PK | Abdul Halim | and | Yearul Kabir |. American Journal of Innovative Research and Applied Sciences. 2015; 1(8):274-279.        | PDF FULL TEXT |

ABSTRACT Background: Hepatitis B virus (HBV) infection is one of the most common public health problems worldwide. The transmission of the hepatitis B virus (HBV) is parenteral, sexual and perinatal. Objectives: The present study was endeavored to appraise the risk factors of HBV positive patients for better understanding of the disease status to enable effective disease interference in Bangladesh and also to analyze the fundamental risk factors. Methods: In this study, 171 adult patients aged of 20-65y recruited from January to June 2014 at Private hospital, Bangladesh. HBV surface antigenemia was reconfirmed by using Enzyme Linked Immunosorbent Assay confirmatory. Results: The mean age of HBV patients was 33.25±11.25y and the mean of hepatitis B surface antigenemia found 5753.53±3407.07 IU/L. As acknowledged, 29.2% female accounted for this study. The highest prevalence of hepatitis B surface antigenemia was in ≥40y (25.1%) followed by 24%, 23.4%, 15.8% and 11.7% in 20-24y, 25-29y, 30-34y and 35-39y age groups respectively. About 45% patients were job holder followed by students (21.6%), housewife (19.9%) and business (13.5%) respectively. In blood groups stratifications, 42.1 % patients raised in O+ve while 22.2 % patients were in B+ve. The rest of 21.1 % and 14.6 % found for A+ve and AB+ve blood type patients respectively.  In respect to blood transfusion history, 5.3 % patient experienced to previous blood transfusion. The mean difference of HBsAg titer distributions in blood groups and age groups found statistically significant (P<0.05) level except sex, working state and transfusion categories. Conclusion: Patient’s age and blood groups found as the major determinant of hepatitis B surface antigenemia in Bangladesh. Keywords: HBsAg, Prevalence, Blood groups, HBV infection.