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| | ARTICLES | Am. J. innov. res. appl. sci. Volume 9, Issue 6, Pages 423-433 (December 2019) |
| Research Article |
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American Journal of innovative
Research & Applied Sciences
Research & Applied Sciences
ISSN 2429-5396 (Online)
OCLC Number: 920041286
OCLC Number: 920041286
| HOME || ABOUT US || ARCHIVES || AIMS AND SCOP || AUTHORS || REVIEW|| SUBMIT MANUSCRIPT || EDITORIAL BOARD || CONTACT US |
| DECEMBER | VOLUME 9 | N° 6 | 2019 |
| Info-AJIRAS-® Journal ISSN 2429-5396 (Online) / Reference CIF/15/0289M |
American Journal of Innovative Research & Applied Sciences
Authors Contact
*Correspondant author and authors Copyright © 2019:
| Casimir Dewanou Akpovi 1,* | and | Antoine Fandohan 2 |
Affiliation.
1. Unité de Recherche sur les Maladies Non Transmissibles et le Cancer (UR-MNTC) | Laboratoire de Rechercher en Biologie Appliquée (LARBA) | Ecole
Polytechnique d’Abomey-Calavi | Université d’Abomey-Calavi | EPAC (UAC), 01BP 2009 Cotonou | Benin |
2. Organisation Non Gouvernementale (ONG) Creuset d’Informations et d’Assistance Communautaire (CIACO BENIN) | Cotonou | Bénin |
This article is made freely available as part of this journal's Open Access: ID | Casimir-Ref.1-ajira071219 |
ABSTRACT
Background: The prevalence of sickle cell trait carriers (AS) is about 30% in some areas of Intertropical Africa and 40% in Central Africa. In Benin, the prevalence of sickle cell trait was estimated at 24%, of which 4.8% had the severe form of the hemoglobinopathy. Despite these alarming statistics, consequent preventive measures are slow to materialize. The present study aimed to develop a strategy for population sensitizing on Sickle Cell Disease (SCD). Methods: The study was carryout in the commune Sô-Ava in southern Benin. It is a lacustrine town of 218 km2 with 118.497 populations. Samples were collected in EDTA. Hemoglobin in the sample was separated by electrophoresis and resulting patterns were scanned on a scanning densitometer. ABO blood groups were determined manually using monoclonal anti-A and anti-B. Results: A pictogram called "Drepastop" was made and used for results expression. Of the 6156 participants, 4403 (71.52%) were non-carriers of SCD traits, 1624 (26.38%) were heterozygous and 129 (2.10%) were homozygous. Of the 1624 heterozygous subjects, 1140 (18.52%) were AS and 484 (7.86%) AC. Among homozygous SCD carriers, 71 (1.15%) were SC, 39 (0.63%) SS and 19 (0.32%) CC. The majority of the study participants, 3167 (51.44%) were blood group O, followed by 1499 (24.35%) group B, 1239 (20.13%) blood group A and 251 (04.08%) blood group AB. Conclusion: The study provided 4403 Green/Green card, 1140 Green/Red, 484 Green/Yellow, 71 Red/Yellow, 39 Red/Red and 19 Yellow/Yellow to the population of Sô-Ava. Our innovation has helped to raise awareness and demystify sickle cell disease. It allowed the population to link "Drepastop" to the choice of spouse.
Keywords: Sickle Cell Disease, pictogram, prevention, Drepastot, Benin.
Background: The prevalence of sickle cell trait carriers (AS) is about 30% in some areas of Intertropical Africa and 40% in Central Africa. In Benin, the prevalence of sickle cell trait was estimated at 24%, of which 4.8% had the severe form of the hemoglobinopathy. Despite these alarming statistics, consequent preventive measures are slow to materialize. The present study aimed to develop a strategy for population sensitizing on Sickle Cell Disease (SCD). Methods: The study was carryout in the commune Sô-Ava in southern Benin. It is a lacustrine town of 218 km2 with 118.497 populations. Samples were collected in EDTA. Hemoglobin in the sample was separated by electrophoresis and resulting patterns were scanned on a scanning densitometer. ABO blood groups were determined manually using monoclonal anti-A and anti-B. Results: A pictogram called "Drepastop" was made and used for results expression. Of the 6156 participants, 4403 (71.52%) were non-carriers of SCD traits, 1624 (26.38%) were heterozygous and 129 (2.10%) were homozygous. Of the 1624 heterozygous subjects, 1140 (18.52%) were AS and 484 (7.86%) AC. Among homozygous SCD carriers, 71 (1.15%) were SC, 39 (0.63%) SS and 19 (0.32%) CC. The majority of the study participants, 3167 (51.44%) were blood group O, followed by 1499 (24.35%) group B, 1239 (20.13%) blood group A and 251 (04.08%) blood group AB. Conclusion: The study provided 4403 Green/Green card, 1140 Green/Red, 484 Green/Yellow, 71 Red/Yellow, 39 Red/Red and 19 Yellow/Yellow to the population of Sô-Ava. Our innovation has helped to raise awareness and demystify sickle cell disease. It allowed the population to link "Drepastop" to the choice of spouse.
Keywords: Sickle Cell Disease, pictogram, prevention, Drepastot, Benin.
*Corresponding author Author & Copyright Author © 2019: | Casimir Dewanou Akpovi | . All Rights Reserved. All articles published in American Journal of Innovative Research and Applied Sciences are the
property of Atlantic Center Research Sciences, and is protected by copyright laws CC-BY. See: http://creativecommons.org/licenses/by-nc/4.0/
| Casimir Dewanou Akpovi 1,* | and | Antoine Fandohan 2 |. Am. J. innov. res. appl. sci. 2019; 9(6): 434-438.
| PDF FULL TEXT | | XML FILE | | Received | November 07, 2019 | | Accepted | December 16, 2019 | | Published | December 20, 2019 |