American Journal of Innovative Research & Applied Sciences
Authors Informations
Instituation affiliation:

1. Faculty of Pharmacy Jinnah | University for women | Karachi | Pakistan |

2. Faculty of Pharmacy | University of Karachi | Pakistan |

3. Drug Regularity Authority of Pakistan/Government of Pakistan | Karachi | Pakistan |
| ABSTRACT | Volume 1, Issue 1, Pages 10-13 (March 2015)
Research Article
    | Naveed S  | Qamar F  | Zainab S  | Sarwar G  |  and  | Tanweer A.M  |. American Journal of Innovative Research and Applied Sciences. 2015; 1(1): 10-13.
ABSTRACT

Background: Fexofenadine is widely used drug for Rhinitis. It is a selective histamine H1 receptor antagonist. Objectives: In our recent research we developed a least time consuming simple and
efficient UV spectrophotometric method for the assay of fexofenadine. Methods: The assay is based on the Ultraviolet Spectroscopy (UV) measuring absorbance maxima at about 220nm
wavelength of fexofenadine. A sample of drug was dissolved in water to produce a solution containing furosemide. Similarly, a sample of ground tablets of two different brands of fexofenadine were
dissolved in water and various dilutions were made. Results: The absorbance of sample preparation was measured at 220nm against the solvent blank. Regression line was obtained for different
dilutions. Conclusion: The analysis shows a linear relationship between absorbance and concentration. Thus the use of UV spectrometry is easy technique to assess fexofenadine concentration.

KEY WORDS: Fexofenadine, spectroscopy, Telefast, Xanidine, UV spectrophotometer.
Authors Copyright © 2015: | 1Naveed S. | 1Qamar F. | 2Zainab S. | 1Sarwar G. | and | 1-3Tanweer A.M.|
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American Journal of innovative
       Research & Applied Sciences 
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ISSN  2429-5396 (Online)
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