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| | ARTICLE | Am. J. innov. res. appl. sci. Volume 12, Issue 2, Pages 55-61 (February 2021) |
| Research Article 2 |
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| FEBRUARY | VOLUME 12 | N° 2 | 2021 |
| Info-AJIRAS-® Journal ISSN 2429-5396 (Online) / Reference CIF/15/0289M |
American Journal of Innovative Research & Applied Sciences
Authors Contact
*Correspondant author and authors Copyright © 2021:
| Marouane Belarbi 1* | Ahmed Alayoud 2 | Ouadie Qamouss 3 | Mohammed Asserraji 1 | Omar Maoujoud 1 |Ahmed Amine Jaouahar 1| and | Nadir Zemraoui 1 |
Affiliation.
1. Service De Néphrologie-Hémodialyse | Hôpital Militaire Avicenne | Faculté de médecine et de pharmacie | Université Cadi Ayyad | Marrakech | Maroc |
2. Laboratoire souss d’anatomie pathologique | Agadir | Maroc |
3. Service de Néphrologie-Hémodialyse | Premier Centre Médico-Chirurgical | Agadir | Maroc |
This article is made freely available as part of this journal's Open Access: ID | Belarbi–Ref25-ajira170221 |
*Correspondant author and authors Copyright © 2021:
| Marouane Belarbi 1* | Ahmed Alayoud 2 | Ouadie Qamouss 3 | Mohammed Asserraji 1 | Omar Maoujoud 1 |Ahmed Amine Jaouahar 1| and | Nadir Zemraoui 1 |
Affiliation.
1. Service De Néphrologie-Hémodialyse | Hôpital Militaire Avicenne | Faculté de médecine et de pharmacie | Université Cadi Ayyad | Marrakech | Maroc |
2. Laboratoire souss d’anatomie pathologique | Agadir | Maroc |
3. Service de Néphrologie-Hémodialyse | Premier Centre Médico-Chirurgical | Agadir | Maroc |
This article is made freely available as part of this journal's Open Access: ID | Belarbi–Ref25-ajira170221 |
Introduction : Aujourd’hui, carrefour de nombreuses disciplines fondamentales, la biopsie rénale apporte un diagnostic, élucide une étiologie, propose un pronostic et une thérapeutique face à une néphropathie. Le but de notre étude était de déterminer la fréquence de cette atteinte ainsi que décrire leurs différentes caractéristiques démographiques, clinico-biologiques et leur profil étiologique. Matériels et méthodes : Ce travail est une étude rétrospective descriptive de 70 PBR (ponction biopsie rénale) réalisées à l’hôpital militaire d’Agadir durant une période de 3 ans, dans le but de décrire le profil des patients atteints de glomérulopathies dans la région d’Agadir. Résultats : Dans cette série, les glomérulopathies sont largement majoritaires. La médiane d’âge était de 41,5 ans avec des extrêmes de 15 et 74 ans. 52,86% des patients étaient de sexe féminin avec une prédominance féminine nette dans la tranche d’âge 45 à 64 ans. La principale indication de PBR est le syndrome néphrotique (54%) suivi de l’atteinte rénale au cours des maladies générales ou systémiques (13%). Les atteintes glomérulaires primitives étaient prédominantes (57%), les atteintes glomérulaires secondaires représentaient 27% et les atteintes vasculaires et tubulo-interstitielles ne représentaient que 12%. Dans les glomérulonéphrites (GN) primitives, la lésion glomérulaire et minime (LGM) était la plus fréquente (40%), suivie par la glomérulonéphrite extra membraneuse (GEM) dans 20% des cas, et la hyalinose segmentaire et focale (HSF) dans 17,5% des cas. La glomérulonéphrite membrano-proliférative ne représentait que 7,5% des cas. Dans les GN secondaires, la néphropathie lupique était la plus fréquente (47,4%), suivie par l’amylose dans 26,3% des cas. Conclusion : La biopsie reste un élément incontournable dans le diagnostic des GN, d’où l’importance d’instaurer un registre national des biopsies rénales. Ces données représentent une contribution importante à l’épidémiologie et à la compréhension des GN à Agadir dans le but de stimuler une nouvelle analyse et améliorer le traitement des GN.
Mots-clés: Biopsie rénale, néphropathies, histologie rénale.
ABSTRACT
Introduction: Currently, renal biopsy is the crossroad of many core fields. In pratical medicine, it provides a diagnosis; propose a prognosis and a treatment for nephropathies. Material and methods: This is a retrospective study of 70 performed at the Military Hospital of Agadir over a period of 3 years, with the aim of describing the profile of patients with glomerulopathies in the region of Agadir. Results: In this study, glomrulopathies as the most important. The median of age was 41.5 years with extremes of 15 and 74 years. 52.86% of patients were female with a clear female predominance between the ages of 45 and 64 years. The main indication of PBR was nephrotic syndrome (54%) followed by renal impairment in general or systemic diseases (13%). Primitive glomerulonephritis were predominant (57%), secondary glomerulonephritis accounted for 27% and vascular injury and tubulointerstitial represented only 12%. In primary glomerulonephritis (GN), minimal change disease (MCD) was the most common (40%), followed by extra membranous glomerulonephritis (MN) in 20% of cases, and focal segmental glomerulosclerosis (FSGS) in 17,5% of cases. Membrano-proliferative glomerulonephritis accounted for only 7.5% of cases. In secondary GN, lupus nephropathy was the most common (47.4%), followed by amyloidosis in 26.3% of cases. Conclusion: Biopsy remains an essential element in the diagnosis of GN, hence the importance of establishing a national registry of kidney biopsies. These data represent an important contribution to the epidemiology and understanding of GN in Agadir with the aim of stimulating new analysis and improving the treatment of GN.
Keywords: Renal biopsy, nephropathies, renal histology.
Mots-clés: Biopsie rénale, néphropathies, histologie rénale.
ABSTRACT
Introduction: Currently, renal biopsy is the crossroad of many core fields. In pratical medicine, it provides a diagnosis; propose a prognosis and a treatment for nephropathies. Material and methods: This is a retrospective study of 70 performed at the Military Hospital of Agadir over a period of 3 years, with the aim of describing the profile of patients with glomerulopathies in the region of Agadir. Results: In this study, glomrulopathies as the most important. The median of age was 41.5 years with extremes of 15 and 74 years. 52.86% of patients were female with a clear female predominance between the ages of 45 and 64 years. The main indication of PBR was nephrotic syndrome (54%) followed by renal impairment in general or systemic diseases (13%). Primitive glomerulonephritis were predominant (57%), secondary glomerulonephritis accounted for 27% and vascular injury and tubulointerstitial represented only 12%. In primary glomerulonephritis (GN), minimal change disease (MCD) was the most common (40%), followed by extra membranous glomerulonephritis (MN) in 20% of cases, and focal segmental glomerulosclerosis (FSGS) in 17,5% of cases. Membrano-proliferative glomerulonephritis accounted for only 7.5% of cases. In secondary GN, lupus nephropathy was the most common (47.4%), followed by amyloidosis in 26.3% of cases. Conclusion: Biopsy remains an essential element in the diagnosis of GN, hence the importance of establishing a national registry of kidney biopsies. These data represent an important contribution to the epidemiology and understanding of GN in Agadir with the aim of stimulating new analysis and improving the treatment of GN.
Keywords: Renal biopsy, nephropathies, renal histology.
*Corresponding author Author & Copyright Author © 2021: | Marouane Belarbi * |. All Rights Reserved. All articles published in American Journal of Innovative Research and Applied Sciences are the property of Atlantic Center Research
Sciences, and is protected by copyright laws CC-BY. See: http://creativecommons.org/licenses/by-nc/4.0/.
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American Journal of innovative
Research & Applied Sciences
Research & Applied Sciences
ISSN 2429-5396 (Online)
OCLC Number: 920041286
OCLC Number: 920041286
ASPECTS EPIDEMIOLOGIQUES, CLINIQUES ET ANATOMOPATHOLOGIQUES DE LA PONCTION-BIOPSIE RENALE DANS LA REGION D’AGADIR-MAROC : A PROPOS DE 70 CAS
EPIDEMIOLOGICAL, CLINICAL AND ANATOMOPATHOLOGICAL ASPECTS OF RENAL PUNCTURE-BIOPSY IN THE AGADIR-MOROCCO REGION: ABOUT 70 CASES
| Marouane Belarbi 1* | Ahmed Alayoud 2 | Ouadie Qamouss 3 | Mohammed Asserraji 1 | Omar Maoujoud 1 |Ahmed Amine Jaouahar 1| and | Nadir Zemraoui 1 |. Am. J. innov. res. appl. sci. 2021; 12(2):43-54.
| PDF FULL TEXT | | XML FILE | | Received | February 10, 2021 | | Accepted | February 20, 2021 | | Published | February 24, 2021 |
EPIDEMIOLOGICAL, CLINICAL AND ANATOMOPATHOLOGICAL ASPECTS OF RENAL PUNCTURE-BIOPSY IN THE AGADIR-MOROCCO REGION: ABOUT 70 CASES
| Marouane Belarbi 1* | Ahmed Alayoud 2 | Ouadie Qamouss 3 | Mohammed Asserraji 1 | Omar Maoujoud 1 |Ahmed Amine Jaouahar 1| and | Nadir Zemraoui 1 |. Am. J. innov. res. appl. sci. 2021; 12(2):43-54.
| PDF FULL TEXT | | XML FILE | | Received | February 10, 2021 | | Accepted | February 20, 2021 | | Published | February 24, 2021 |